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Excretion of Ascaris lumbricoides following reduced-intensity allogeneic hematopoietic stem cell transplantation and consecutive treatment with mebendazole.

Identifieur interne : 000122 ( Main/Exploration ); précédent : 000121; suivant : 000123

Excretion of Ascaris lumbricoides following reduced-intensity allogeneic hematopoietic stem cell transplantation and consecutive treatment with mebendazole.

Auteurs : Verena Luber [Allemagne] ; Mathias Lutz [Allemagne] ; Marianne Abele-Horn [Allemagne] ; Hermann Einsele [Allemagne] ; Götz Ulrich Grigoleit [Allemagne] ; Stephan Mielke [Allemagne, Suède]

Source :

RBID : pubmed:31782899

Descripteurs français

English descriptors

Abstract

Here, we present the unique case of a 51-year-old German patient with multiple myeloma excreting Ascaris lumbricoides in his stool five weeks after allogeneic hematopoietic stem cell transplantation. Stool analysis remained negative for the presence of eggs, and there was no eosinophilia in the peripheral blood at any time around stem cell transplantation. The patient was commenced on a three-day treatment with mebendazole, which was well tolerated. No serious interactions with the concomitant post-transplant medication or negative effects on the hematopoiesis were observed, and the myeloma still is in complete remission. To our knowledge, this is the first report on excretion of A lumbricoides in the context of allogeneic stem cell transplantation. The case is remarkable with view to the fact that the parasite has supposedly survived all courses of myeloma treatment including autologous and allogeneic conditioning. Parasitosis with A lumbricoides has a worldwide prevalence of about a billion and is extremely rare in northern Europe. Possibly the patient got infected during a trip to Egypt years before multiple myeloma was diagnosed.

DOI: 10.1111/tid.13224
PubMed: 31782899


Affiliations:


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Le document en format XML

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<term>Ascaris lumbricoides (MeSH)</term>
<term>Egypt (MeSH)</term>
<term>Feces (parasitology)</term>
<term>Hematopoietic Stem Cell Transplantation (MeSH)</term>
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<div type="abstract" xml:lang="en">Here, we present the unique case of a 51-year-old German patient with multiple myeloma excreting Ascaris lumbricoides in his stool five weeks after allogeneic hematopoietic stem cell transplantation. Stool analysis remained negative for the presence of eggs, and there was no eosinophilia in the peripheral blood at any time around stem cell transplantation. The patient was commenced on a three-day treatment with mebendazole, which was well tolerated. No serious interactions with the concomitant post-transplant medication or negative effects on the hematopoiesis were observed, and the myeloma still is in complete remission. To our knowledge, this is the first report on excretion of A lumbricoides in the context of allogeneic stem cell transplantation. The case is remarkable with view to the fact that the parasite has supposedly survived all courses of myeloma treatment including autologous and allogeneic conditioning. Parasitosis with A lumbricoides has a worldwide prevalence of about a billion and is extremely rare in northern Europe. Possibly the patient got infected during a trip to Egypt years before multiple myeloma was diagnosed.</div>
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<Reference>
<Citation>Idris OA, Wintola OA, Afolayan AJ. Helminthiases; prevalence, transmission, host-parasite interactions, resistance to common synthetic drugs and treatment. Heliyon. 2019;5:e01161.</Citation>
</Reference>
<Reference>
<Citation>Omrani VF, Fallahi S, Rostami A, et al. Prevalence of intestinal parasite infections and associated clinical symptoms among patients with end-stage renal disease undergoing hemodialysis. Infection. 2015;43:537-544.</Citation>
</Reference>
<Reference>
<Citation>Palumbo A, Avet-Loiseau H, Oliva S, et al. Revised international staging system for multiple myeloma: a report from international myeloma working group. J Clin Oncol. 2015;33:2863-2869.</Citation>
</Reference>
<Reference>
<Citation>Mai EK, Bertsch U, Durig J, et al. Phase III trial of bortezomib, cyclophosphamide and dexamethasone (VCD) versus bortezomib, doxorubicin and dexamethasone (PAd) in newly diagnosed myeloma. Leukemia. 2015;29:1721-1729.</Citation>
</Reference>
<Reference>
<Citation>Wright JE, Werkman M, Dunn JC, Anderson RM. Current epidemiological evidence for predisposition to high or low intensity human helminth infection: a systematic review. Parasit Vectors. 2018;11:65.</Citation>
</Reference>
<Reference>
<Citation>Lakshmi SP, Palaniappan N, Arunagiri A. Ascariasis: challenges in the diagnosis of single worm disease. J Indian Med Assoc. 2013;111:621-622.</Citation>
</Reference>
<Reference>
<Citation>Khuroo MS. Ascariasis. Gastroenterol Clin North Am. 1996;25:553-577.</Citation>
</Reference>
<Reference>
<Citation>Lamberton PH, Jourdan PM. Human ascariasis: diagnostics update. Curr Trop Med Rep. 2015;2:189-200.</Citation>
</Reference>
<Reference>
<Citation>Mejia R, Nutman TB. Evaluation and differential diagnosis of marked, persistent eosinophilia. Semin Hematol. 2012;49:149-159.</Citation>
</Reference>
<Reference>
<Citation>Sharma M, Showkat A, Somani P. An unusual cause of biliary colic. Gastroenterology. 2017;153:e1-e2.</Citation>
</Reference>
<Reference>
<Citation>Avery RH, Wall LA, Verhoeve VI, Gipson KS, Malone JB. Molecular confirmation of Ascaris suum: further investigation into the zoonotic origin of infection in an 8-year-old boy with loeffler syndrome. Vector Borne Zoonotic Dis. 2018;18:638-640.</Citation>
</Reference>
<Reference>
<Citation>Behm CA, Ovington KS. The role of eosinophils in parasitic helminth infections: insights from genetically modified mice. Parasitol Today. 2000;16:202-209.</Citation>
</Reference>
<Reference>
<Citation>Aleksandra L, Barbara Z, Natalia LA, Danuta KB, Renata GK, Ewa ML. Respiratory failure associated with Ascariasis in a patient with immunodeficiency. Case Rep Infect Dis. 2016;2016:4070561.</Citation>
</Reference>
<Reference>
<Citation>Jurcic JG, Koll B, Brown AE, Crown JP, Yahalom J, Gulati SC. Excretion of Ascaris lumbricoides during total body irradiation. Bone Marrow Transplant. 1994;13:491-493.</Citation>
</Reference>
<Reference>
<Citation>Panic G, Duthaler U, Speich B, Keiser J. Repurposing drugs for the treatment and control of helminth infections. Int J Parasitol Drugs Drug Resist. 2014;4:185-200.</Citation>
</Reference>
<Reference>
<Citation>Cao S, Aboge GO, Terkawi MA, et al. Mycophenolic acid, mycophenolate mofetil, mizoribine, ribavirin, and 7-nitroindole inhibit propagation of Babesia parasites by targeting inosine 5'-monophosphate dehydrogenase. J Parasitol. 2014;100:522-526.</Citation>
</Reference>
<Reference>
<Citation>Azevedo LS, Castro MC, Paula FJ, Ianhez LE, David-Neto E. Mycophenolate mofetil may protect against Pneumocystis carinii pneumonia in renal transplanted patients. Rev Inst Med Trop Sao Paulo. 2005;47:143-145.</Citation>
</Reference>
<Reference>
<Citation>Lutz M, Mielke S. New perspectives on the use of mTOR inhibitors in allogeneic haematopoietic stem cell transplantation and graft-versus-host disease. Br J Clin Pharmacol. 2016;82:1171-1179.</Citation>
</Reference>
<Reference>
<Citation>Khadir F, Shaler CR, Oryan A, et al. Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin. PLoS Negl Trop Dis. 2018;12:e0006701.</Citation>
</Reference>
<Reference>
<Citation>Mejia P, Trevino-Villarreal JH, Reynolds JS, et al. A single rapamycin dose protects against late-stage experimental cerebral malaria via modulation of host immunity, endothelial activation and parasite sequestration. Malar J. 2017;16:455.</Citation>
</Reference>
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